AASTY Screening Kit

Each membrane proteins has its own native lipid environment. Therefore, each lipid environment is unique to each membrane protein. And it is this lipid environment that synthetic polymers like AASTYs interact with. Therefore one needs a broader selection of polymers, since there is not one AASTY that fits each phospholipid composition. To address this question AASTYs come in three different ratios of acrylic acid to styrene. The ratios differ in hydrophilic property of AASTY which results in different affinities to varying membrane lipid compositions. The second feature to screen for when it comes to AASTY is the size of the resulting nanodiscs. One of AASTY's greatest features compared to SMA or DIBMA, is that its nanodiscs are quite uniformous in size. Therefore the correct fitting nanodisc size must be determined in before.