GentleLys - Native Cell Lysis Buffer - Dissolve

The Cube Biotech GentleLys Buffer is the only 100% detergent-free, non-denaturing solution to lyse cultured cells from plated cells as well as cells pelleted from suspension cultures while solubilizing all membranes in the process. GentleLys enables the extraction of soluble proteins and the stabilization of membrane proteins from all compartments of the cells. It is compatible with many applications, including Immunoassays, Protein Assays, Mass Spectrometry, and Protein Purification.

The Buffer comes in two variants: GentleLys – Dissolve which lyses cells in 15 min while GentleLys – Stabilize lyses all cells and makes the whole proteome (soluble and membrane proteins) of the cell available for your analytic approaches. It solubilizes all membranes and stabilizes expressed membrane proteins in their native conformation

They are able to do this thanks to the inclusion of synthetic nanodisc copolymers.