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Neuromics

Protein Stabilization

SMALP 140

Description

The synthethic polymer SMALP 140, among our other synthetic nanodisc products has been developed for for the solubilization & subsequent purification of membrane proteins from all kinds of cell membranes. SMALP products do this by using the phospholipids around the membrane proteins and form them into a disc-shaped structure in which the membrane proteins are centered. SMALP 140 + its corresponding buffer are shipped in a lyophilized state, so they have to be dissolved in dH2O. Then the product is ready-to-use. SMALP 140 has a amber color in solution. We recommend using affinity chromatography for the follow-up purification of the membrane protein of interest. For membrane protein purification we recommend to use the Rho1D4-tag.

Features

State: Lyophilized Powder, to be solved with water

Polymer styrene-to-maleic anhydride ratio: 1.4:1

Molecular weight: 5,000 Da

pH after solving: 7.5

Solubility: 45 %

Divalent cationic tolerance: < 5 mM

Color: Amber

Odor: Odorless

Freeze-thaw stable?: Yes

Shipping Temperature: ambient temperature

Storage of lyophilized copolymer: -20°C for several years

Storage of dissolved copolymer: 2-8°C for several days

SMALP 140

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For research use only. Not for diagnostic or clinical use.