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Neuromics

Protein Stabilization

SMALP BZ25

Description

The SMALP BZ series was developed by Cube Biotech in collaboration with Prof. Bert Klumperman from Nanosene, a spinout company of Stellenbosch University in South Africa. The goal was to create SMALPs that are synthesized via RAFT polymerization, achieving a better defined polymer size and a low dispersity (narrow chain length distribution). This is a significant improvement over previous SMALPs. The SMALP BZs are thus more efficient in dissolving the cell membranes and increasing protein yield.

After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag.

Features

Usage: Membrane protein solubilization & stabilization

Full-Name: Poly(styrene-co-maleic acid-co-25%(N-benzyl)maleimide) copolymer, sodium salt in 50 mM HEPES, pH 7.5

Formula Weight: 5,500 g/mol

Buffer: 50 mM HEPES

pH: 7.5

State: Lyophilized Powder

Recommended concentration range upon use: 1% to 5%

Solubility: > 10 % in H2O

Color: White to slightly yellow

Odor: Odorless

Shipping Temperature: ambient temperature“

Long-term Storage (lyophilized copolymer): -20°C for several years

Short-term Storage (dissolved copolymer): 2-8°C for several days

SMALP BZ25

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For research use only. Not for diagnostic or clinical use.