DIBMA 6

This new version of the classical DIBMAs 10 and 12 differs in its size and synthetization process.

The new DIBMA 6 is not only smaller than its predecessors (DIBMA 10 and DIBMA 12) but, together with Sulfo-DIBMA, belongs to a new generation of DIBMA’s that are RAFT polymerized. This achieves a reduction in both monomer size and lower polydispersity, meaning that if you need your copolymers to all have a similar size this is the copolymer to choose.

With DIBMA 6 you can directly extract membrane proteins from cells without an intermediate step of detergent solubilization, like with SDS which would usually interfere with your target protein's function. Another advantage of DIBMA 6 is the lack of an absorbance maxima at 280 nm. SMAs, in comparison, usually interfere with protein quantification, as aromatic amino acids absorb at the same spectrum.

Features

State: Lyophilized Powder, to be solved with water

Full Name: Diisobutylene Maleic Acid in 50 mM HEPES, pH 7.5

Buffer: HEPES

pH after solving: 7.5

pH Stability of Copolymer: 5.0-10

Absorbance at 280nm: No

Molecular Weight: 6 kDA

Ca2+ tolerance: 40 mM

Mg2+ tolerance: 50 mM

Solubility: > 10% (H2O)

Polymerization Type: RAFT

Shipping Temperature: Ambient Temperature

Storage of lyophilized copolymer: -20°C for several years

Storage of dissolved copolymer: 2-8°C for several days