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Neuromics

Protein Stabilization

DIBMA 6 Biotin

Description

The new DIBMA 6 is not only smaller than its predecessors (DIBMA 10 and DIBMA 12) but together with Sulfo-DIBMA belongs to a new generation of DIBMA’s which are RAFT polymerized. This achieves a reduction in both monomer size and lower polydispersity, meaning that if you need your copolymers to all have a similar size this is the copolymer to choose.

This first-of-its-kind, functionalized version of DIBMA 6 is tagged with biotin, enabling tag-free solubilization and stabilization of your target protein. There is no protein-labeling required, and the accesibility to the ecto- and cytoplasmatic domain is preserved.

This functionalized copolymer is particularly suited for downstream applications that require copolymer stabilization without affecting the protein. These include drug screening, high-throughput processes and assay development.

Features

State: Lyophilized Powder, to be solved with water

Full Name: Diisobutylene Maleic Acid Biotin in 50 mM HEPES, pH 7.5

Buffer: HEPES

pH after solving: 7.5

pH Stability of Copolymer: 5.0-10

Absorbance at 280nm: N/A

Molecular Weight: 6 kDA

Ca2+ tolerance: 30 mM

Mg2+ tolerance: 40 mM

Solubility: > 10% (H2O)

Polymerization Type: RAFT

Shipping Temperature: Ambient Temparature

Storage of lyophilized copolymer: -20°C for several years

Storage of dissolved copolymer: 2-8°C for several days

DIBMA 6 Biotin

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For research use only. Not for diagnostic or clinical use.