Human Dermal Fibroblasts (Type 1 Diabetes)

Human Dermal Fibroblasts from Type 1 Diabetes donors are isolated from the dermal layer of skin tissue obtained from donors with a clinically confirmed diagnosis of Type 1 Diabetes Mellitus. These cells are cryopreserved at the earliest possible passage to preserve their in vivo-like characteristics and disease-specific phenotype.

HDFs are the principal architects of the extracellular matrix (ECM) and play a critical role in wound healing, inflammation, and tissue integrity. HDFs from a T1D background provide a vital model for studying the cellular and molecular mechanisms underlying impaired wound healing, a severe and common complication of diabetes. These cells may exhibit altered proliferation, migration, ECM remodeling, and inflammatory responses, making them essential for diabetes research, drug discovery, and the study of diabetic complications.

Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.