Cas9-Human Glomerular Microvascular Endothelial Cells

Cas9 is an enzyme commonly used in the CRISPR-Cas9 gene editing system to cut DNA at specific locations. Stable expression of Cas9 is desirable in gene editing experiments, as it allows for precise and consistent genome editing.

Human glomerular microvascular endothelial cells (HGMECs) have been genetically modified to express Cas9 protein in a stable manner. This means that the cells have been engineered to continuously produce and maintain the expression of the Cas9 protein over time. These cells were isolated from the normal human kidney glomeruli tissue before Cas9 protein was introduced into the cell. The stable expression enables researchers to make targeted changes to the genome of the cell.

Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.