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Neuromics
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Primary Antibody · Rabbit IgG

Calbindin D-28K

Species
Mouse, Rat
Applications
IHC, IF

Description

Calbindin-D, also known as Calbindin 1, is a Vitamin D-dependent cytoplasmic protein in the EF-hand calcium binding protein family that includes calmodulin, parvalbumin, troponin C, and S100. Calbindin-D is widely expressed and regulates calcium homeostasis. Calbindin-D protects neurons from excitotoxic and apoptotic cell death by buffering excess calcium. Human, mouse, and rat Calbindin-D share 99% amino acid sequence identity
IHC image of neurons staining for the calbindin in the rat cortex. The tissue was fixed with 4% formaldehyde in 0.1 M phosphate buffer, before being removed and prepared for vibratome sectioning.
IHC image of neurons staining for the calbindin in the rat cortex. The tissue was fixed with 4% formaldehyde in 0.1 M phosphate buffer, before being removed and prepared for vibratome sectioning.

For research use only. Not for diagnostic or clinical use.