Published with this product (2)
2023Preprints
Regulation of Primary Cilia Length by O-GlcNAc during Neuronal Development in Human Neuron Model
Jie L. Tian, Chia-Wei Huang, Farzad Eslami, Michael Philip Mannino, Rebecca Lee Mai, and Gerald W. Hart
doi:10.20944/preprints202304.0345.v12023Bioactive Materials, 23:300-313
Bai Xu, Man Yin, Yaming Yang, Yunlong Zou, Wenbin Liu, Lianyong Qiao, Jixiang Zhang, Zhan Wang, Yayu Wu, He Shen, Minghan Sun, Weiyuan Liu, Weiwei Xue, Yongheng Fan, Qi Zhang, Bing Chen, Xianming Wu, Ya Shi, Falong Lu, Yannan Zhao, Zhifeng Xiao, and Jianwu Dai
doi:10.1016/j.bioactmat.2022.11.008
Description
Nestin is a member of the class IV intermediate filament protein family which is expressed in neuroepithelial stem cells. The protein proved to be an unusual member of the intermediate filament family, containing an α-helical region homologous to that found in keratin and neurofilament subunits. The nestin protein has a very short non-helical N-terminal region followed by the α-helical region and a very long and repetitive C-terminal region. Nestin is expressed by radial glia and other types of dividing cells in the developing central and peripheral nervous systems and in developing muscle.
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For research use only. Not for diagnostic or clinical use.