Published with this product (2)
2024Cell Death & Disease, 15:464
Humanin Activates Integrin αV–TGFβ Axis and Leads to Glioblastoma Progression
Cuong P. Ha, Tuyen N.M. Hua, Vu. T.A. Vo, Jiyeon Om, Sangwon Han, Seung-Kuy Cha, Kyu-Sang Park, and Yangsik Jeong
doi:10.1038/s41419-024-06790-82023Research Square
Humanin Activates Integrin αV-TGFβ Axis and Leads to Glioblastoma Progression
Yangsik Jeong, Tuyen Hua, Vu Vo, Jiyeon Om, Sangwon Han, Seung-Kuy Cha, Kyu-Sang Park, and Cuong Ha
doi:10.21203/rs.3.rs-2702693/v1
Description
Humanin (HN) encodes a polypeptide that appears to protect neurons from both cytotoxic and apoptotic cell death in Alzheimer’s disease. Analogues of the HN peptide have been shown to spare memory in animal models of Alzheimer’s, suggesting its potentially important therapeutic role. It is found in highest levels in testis, colon, and AD-affected brain tissues.
We currently have tested the antibody by Western blotting against the human HN peptide and cell lysates of 293T cells transfected with a GFP tagged HN.
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For research use only. Not for diagnostic or clinical use.