Published with this product (4)
2015Gynecol Obstet Invest
Guo J, Gao J, Yu X, Luo H, Xiong X, Huang O
doi:10.1159/0003655692009Toxicology Letters, Volume 184, Issue 3, Pages 186-191
Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes
Amanda K. Ashley, William H. Hanneman, Takeshi Katoh, Julie A. Moreno, Ashley Pollack, Ronald B. Tjalkens, and Marie E. Legare
doi:10.1016/j.toxlet.2008.11.0082009Neurobiology of Disease, Volume 33, Issue 1, Pages 28-36
DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone
Steven J. Mullett and David A. Hinkle
doi:10.1016/j.nbd.2008.09.0132008Journal of Neurochemistry, 105(6):2435-2453
Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease
Liu, Fang; Nguyen, Jamie L.; Hulleman, John D.; Li, Li; Rochet, Jean-Christophe
doi:10.1111/j.1471-4159.2008.05333.x
Description
Four chromosomal loci (PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. Positional cloning within the refined PARK7 critical region recently identified mutations in the DJ-1 gene in PARK7-linked families. Mutations in the PARK7/DJ-1 gene cause autosomal-recessive Parkinson’s disease.
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