Published with this product (18)
2021
Genetic Deletion of β-Arrestin 2 Modulates LSD Stimulated Behaviors in Mice
Ramona M. Rodriguiz, Vineet Nadkarni, Christopher R. Means, Vladimir M. Pogorelov, Yi-Ting Chiu, Bryan L. Roth, and William C. Wetsel
doi:10.21203/rs.3.rs-544199/v12021Journal of Neurophysiology
Lauren F. Borkowski, Catherine L. Smith, Amy N. Keilholz, and Nicole L. Nichols
doi:10.1152/jn.00236.20212021Indiana University, Doctoral Dissertation
A New Mechanism of Serotonin Transporter Regulation by Simvastatin and the Isoprenylation Pathway
Carmen Marie Deveau
2021Scientific Reports, 11:17690
LSD-Stimulated Behaviors in Mice Require β-Arrestin 2 but Not β-Arrestin 1
Ramona M. Rodriguiz, Vineet Nadkarni, Christopher R. Means, Vladimir M. Pogorelov, Yi-Ting Chiu, Bryan L. Roth, and William C. Wetsel
doi:10.1038/s41598-021-96736-32020Respiratory Physiology & Neurobiology
5-HT2A/B Receptor Expression in the Phrenic Motor Nucleus in a Rat Model of ALS (SOD1G93A)
Lauren F. Borkowski, Taylor A. Craig, Olivia E. Stricklin, Katherine A. Johnson, and Nicole L. Nichols
doi:10.1016/j.resp.2020.103471
Description
The affinity purified histochemical antibody for 5HT2A receptor was generated in rabbit against a multiple antigenic peptide of an N-terminal synthetic sequence corresponding to amino acids 22-41 of rat 5HT2A receptor.
The antibody produces 4+ (maximum) immunolabeling of 5HT2A receptor at dilutions of 1/300 - 1/500 using biotin-streptavidin/HRP technique with free-floating methods on rat cortex, amygdala and hippocampus. The addition of intensifying reagents such as nickel ammonium sulfate to the chromogen solution allows further dilution to approximately 1/1,000 or more. Optimal dilution will vary depending upon fixation, labeling technique and/or detection system; therefore, a dilution series is recommended. Immunolabeling is completely abolished by preadsorption with synthetic rat 5HT2A receptor (22-41). Immunolabeling of Western blot revealed a single band of approximately between 55 and 75 kDA. For Western Blot Protocol See: DOI:10.1124/jpet.111.18378.
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For research use only. Not for diagnostic or clinical use.