Name: proDynorphin
Brand: Neuromics
SKU: GP10110
Price: 475.00 USD

Published with this product (20)

2023Journal of Bone Oncology, 100510
Evaluation of Pain Related Behaviors and Disease Related Outcomes in an Immunocompetent Mouse Model of Prostate Cancer Induced Bone Pain
Juan Miguel Jimenez-Andrade Martha B. Ramírez-Rosas, Sun Hee Park, Renee Parker, Matthew R. Eber, Rebecca Cain, Mary Newland, Fang-Chi Hsu, Carol A. Kittel, Thomas J. Martin, Enriqueta Muñoz-Islas, Yusuke Shiozawa, and Christopher M. Peters
doi:10.1016/j.jbo.2023.100510
2023Current Research in Neurobiology, 100107
Delta 9-Tetrahydrocannabinol Does Not Upregulate an Aversive Dopamine Receptor Mechanism in Adolescent Brain Unlike in Adults
Marie-Eve Di Raddo, Marija Milenkovic, Meenalochani Sivasubramanian, Ahmed Hasbi, Jack Bergman, Sarah Withey, Bertha K. Madras, and Susan R. George
doi:10.1016/j.crneur.2023.100107
2021
Activation of Transient Receptor Potential Vanilloid 1 Channels in the Nucleus of the Solitary Tract and Activation of Dynorphin Input to the Median Preoptic Nucleus Contribute to Impaired BAT Thermogenesis in Diet Induced Obesity. eNeuro
Ellen P. S. Conceicao, Christian Reynolds, Shaun F. Morrison, and Christopher J. Madden
doi:10.1523/ENEURO.0048-21.2021
2021Handbook of Experimental Pharmacology
Considerations on Using Antibodies for Studying the Dynorphins/Kappa Opioid Receptor System
Chong guang Chen, Melanie Widmann, Christoph Schwarzer, and Lee-Yuan Liu-Chen
doi:10.1007/164_2021_467
2020Neurobiology of Stress
A Projection from the Paraventricular Nucleus of the Thalamus to the Shell of the Nucleus Accumbens Contributes to Footshock Stress-Induced Social Avoidance
Xinwen Dong, Sa Li, and Gilbert J. Kirouac
doi:10.1016/j.ynstr.2020.100266

Description

Dynorphin peptides are members of the opioid peptide family and contain the canonical opioid sequence Tyr-Gly-Gly-Phe. These peptides are derived from prodynorphin and include dynorphin A, dynorphin B and alpha neo-endorphin. Of the opioid peptides, the dynorphins have the highest affinity for the kappa opioid receptor. They are found distributed throughout the nervous system and play a role in many physiological functions.

Systemic artemin normalized immunohistochemical markers in the ipsilateral L5 DRG, dorsal spinal cords and sciatic nerves of SNL rats.Immunofluorescent labeling was done 14 d after sham or SNL surgery and treatment with vehicle or artemin starting on day 3 after surgery. Scale bar = 100 um for DRG (first two rows), 50 mum for sciatic nerve (third row) and 200 mum for spinal cord (bottom row). Nature Medicine 9, 1383 - 1389

Dr Patrick Mantyh et al have successfully used this antibody to stain mouse spinal cord tissue. see J Pain Symptom Manage. 2008 September; 36(3): 289–303.

Immuofluorescent detection of Prodynorphin (seen as immunoreactive varicosities) in art hypothalamus (red fluorescence).

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What this product needs to grow and work as described.

proDynorphin
P10116 · 100 ug Blocking Peptide$95.00

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For research use only. Not for diagnostic or clinical use.