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Neuromics

Primary Antibody · Guinea Pig IgG

VR1 C-terminus (TRPV1)

Cited in 57 papers
Species
Human, Rat
Applications
IHC

Published with this product (57)

All 57 publications

Description

VR1 (vanilloid receptor 1) is a channel activated by capsaicin, the pungent ingredient in hot peppers. It was isolated from sensory neurons. Sequence analysis suggests that VR1 has six transmembrane domains and intracellular N- and C-termini. It shares structural similarities with the family of putative store-operated calcium channels. VR1 is expressed by nociceptive sensory neurons. It is activated by noxious heat and is thought to function as transducer of noxious thermal stimuli.

Product Highlights:

TRPV1 staining of mouse inferior olive using Cy3-conjugated donkey anti-guinea pig secondary antibodies (red color) and DAPI (blue) as a nuclear counterstain.
TRPV1 staining of mouse inferior olive using Cy3-conjugated donkey anti-guinea pig secondary antibodies (red color) and DAPI (blue) as a nuclear counterstain.
VR1-C staining of rat dorsal horn (dilution 1:100).
VR1-C staining of rat dorsal horn (dilution 1:100).
VR1 C-terminus (TRPV1)
(J Dent Res 85(1):49-53, 2006) : Evaluation of the expression patterns of TLR4 and CD14 in trigeminal sensory neurons. White arrows depict examples of neurons expressing both markers for each row of three images, and yellow arrows depict examples of neurons that express one but not both markers.
(J Dent Res 85(1):49-53, 2006) : Evaluation of the expression patterns of TLR4 and CD14 in trigeminal sensory neurons. White arrows depict examples of neurons expressing both markers for each row of three images, and yellow arrows depict examples of neurons that express one but not both markers.

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For research use only. Not for diagnostic or clinical use.