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Neuromics

Primary Antibody · Rabbit IgG

FABP7

Species
Mouse, Rat
Applications
WB, IHC, IF

Description

Fatty Acid-Binding Proteins (FABPs) are a family of low-molecular-weight (14–15kDa) intracellular polypeptides that bind and solubilize long-chain fatty acids, thus controlling intracellular lipid dynamics (1,2). Ten members of the FABP family are expressed in humans, each with a specific cell and tissue expression pattern. The seventh member of the family is generally called FABP7 but is also known as brain lipid binding protein or BLBP. FABP7 is abundantly expressed in neural stem cells, radial glia and astrocytes of the developing brain and the retina but is heavily down regulated in the adult.

Immunofluorescent analysis rat embryonic brain section stained with rabbit pAb to FABP7, RA22137, dilution 1:1,000 in red. The blue is Hoechst staining of nuclear DNA. The FABP7 antibody stains developing astrocytes and radial glial cells.
Immunofluorescent analysis rat embryonic brain section stained with rabbit pAb to FABP7, RA22137, dilution 1:1,000 in red. The blue is Hoechst staining of nuclear DNA. The FABP7 antibody stains developing astrocytes and radial glial cells.
Western blot analysis of whole brain and neuron-glial cell culture lysates using rabbit pAb to FABP7, RA22137, dilution 1:2,000 in green, and mouse mAb to β-tubulin, MCA-1B12, dilution 1:10,000 in red: [1] protein standard, [2] adult rat brain, [3] E18 embryonic rat brain, [4] rat neuron-glial cell culture and [5] adult mouse brain lysates.
Western blot analysis of whole brain and neuron-glial cell culture lysates using rabbit pAb to FABP7, RA22137, dilution 1:2,000 in green, and mouse mAb to β-tubulin, MCA-1B12, dilution 1:10,000 in red: [1] protein standard, [2] adult rat brain, [3] E18 embryonic rat brain, [4] rat neuron-glial cell culture and [5] adult mouse brain lysates.

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For research use only. Not for diagnostic or clinical use.