Description
DNA damaging and crosslinking agent [1]. Induces apoptosis in various cell lines [2]. Cell permeable [3].
References:
1) Tee and Proud (2000), DNA-damaging agents cause inactivation of translational regulators linked to mTOR signaling; Oncogene, 30 21
2) Park et al. (2000), Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95- independent manner in human gastric adenocarcinoma cells ; Cancer Lett., 158 125
3) Merck Index 14:6215
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For research use only. Not for diagnostic or clinical use.