Description
Activates protein kinase C (10-100 ng/ml) [1]. May display PKC-independent effects in various cell types [2].
Warning: Skin irritant. Avoid contact with this compound [3].
References:
1) Saraiva et al. (2004), characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay; Eur. J. Pharmacol., 491 101
2) Doerner et al. (1990), Protein kinase C-dependent and –independent effects of phorbol esters on hippocampal calcium channel current; J. Neurosci., 10 1699
3) Merck Index 14:7332
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For research use only. Not for diagnostic or clinical use.