Description
Nafamostat mesylate, although reversible, is a powerful serine protease inhibitor (IC50's range from 0.3 - 54.0 μM). It inhibits the demethylase activity of the fat mass and obesity-associated protein (FTO) (1).
References:
1) Han et al. (2019) Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase; Chemico-Biological Interactions, 297 80
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For research use only. Not for diagnostic or clinical use.