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Neuromics

Small Compound/Modulator · Modulator

Apomorphine HCl

Description

Archetypal dopamine pan-receptor agonist. Displays anti-Parkinsons activity in vivo [1,2]. Protects against MPTP-induced neurotoxicity in a mouse model [3]. In clinical use for Parkinson’s disease [4,5].

References:

1) Merck Index 14:746

2) MJ Millan  et al. J. Pharmacol. Exp. Ther. 2002 303:791

3) E Grunblatt et al. Mov. Disord.  1999 14:612

4) M Auffret et al. J. Neurol. Sci.  2017 372:279

5) P Jenner and R Katzenschlager Parkinsonism. Relat. Disord.  2016 33 Suppl 1:S13

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For research use only. Not for diagnostic or clinical use.